Psychedelic therapy and the conventional utilization of hallucinogens has been followed back to a large number of years. They are profoundly imbued in numerous societies and religions from around the globe. Proof has been found of peyote in Mesoamerica, psychoactive mushrooms in Mexico, ayahuasca in the Amazon, and cannabis in the old populaces of Central Asia and India. This customary utilization of hallucinogens was (and stays) restricted to explicit societies and has never observed broad use.