Lowes.syf.com/activate is a convenient platform for activating your Lowe's credit card. Simply visit the website and follow the easy steps to activate your card quickly. Once... moreLowes.syf.com/activate is a convenient platform for activating your Lowe's credit card. Simply visit the website and follow the easy steps to activate your card quickly. Once activated, you can start using your Lowe's credit card for purchases both in-store and online.