Abiraterone acetate is a medication used in the treatment of prostate cancer, particularly in cases that are resistant to other hormone therapies and have metastasized (spread to... moreAbiraterone acetate is a medication used in the treatment of prostate cancer, particularly in cases that are resistant to other hormone therapies and have metastasized (spread to other parts of the body). Here are some key points regarding its effectiveness:
Mechanism of Action: Abiraterone acetate works by inhibiting the production of androgens (male hormones) in the body, including testosterone, which fuels the growth of prostate cancer cells. It does this by blocking an enzyme called CYP17A1, which is involved in the synthesis of androgens.
Clinical Use: Abiraterone acetate is primarily used in combination with another medication called prednisone or prednisolone. This combination therapy is effective in reducing tumor size, slowing cancer progression, and improving survival rates in patients with metastatic castration-resistant prostate cancer (mCRPC).
Effectiveness: Clinical trials and real-world studies have shown that abiraterone acetate, when used as part of standard treatment regimens,... less