SAN FRANCISCO Malcolm Butler Jersey , June 11 (Xinhua) -- Researchers at the University of California, San Francisco, have drawn a link between distinctive genetic... more
SAN FRANCISCO Malcolm Butler Jersey , June 11 (Xinhua) -- Researchers at the University of California, San Francisco, have drawn a link between distinctive genetic abnormalities in some neurodegenerative diseases and the formation of "RNA foci," abnormal clusters of ribonucleic acid (RNA) molecules that accumulate in the cell nucleus.
The presence of RNA foci is a prominent feature of a group of deadly inherited neurodegenerative diseases, including Huntington's disease, certain forms of amyotrophic lateral sclerosis (ALS) Austin Johnson Jersey , and frontotemporal dementia.
While many researchers believe that these clusters are toxic to nerve cells, it has not been clear how or why they form.
Published online recently in the journal Nature, the new study focused on a group of disorders known as "repeat expansion" diseases. In these conditions, short strings of the deoxyribonucleic acid (DNA) "letters" known as nucleotides are abnormally repeated several times.
Over the course of an... less