Silagra 50 mg, which contains sildenafil (the same active ingredient as Viagra), should typically be taken about 30 minutes to 1 hour before sexual activity. Silagra 50 mg allows enough time for the medication to start working. However, the exact timing can vary depending on individual response and other factors. It's a good idea to follow the instructions provided by your healthcare provider or the guidelines on the medication's label. If you have any concerns or questions about using Silagra, consulting with a healthcare professional is always a good approach.