Zhewitra 40 mg, which contains vardenafil as its active ingredient, is a medication used to treat erectile dysfunction by improving blood flow to the penis. While vardenafil is generally safe for most men when taken as prescribed, it may pose cardiovascular risks in individuals with pre-existing heart conditions. Though rare, there have been reports of serious cardiovascular events like heart attack or stroke associated with the use of phosphodiesterase type 5 (PDE5) inhibitors, particularly in those with underlying cardiovascular disease. Zhewitra 40 mg can also cause a drop in blood pressure, especially if taken with nitrates or certain medications, which might increase stroke risk. Always consult a doctor before use.