Generic Duratia tablets, which contain the active ingredient tadalafil, are generally considered safe for most men when used according to a doctor’s prescription. They are commonly prescribed for erectile dysfunction (ED) and work by increasing blood flow to the penis, helping achieve and maintain an erection. However, safety depends on individual health conditions. Men with heart problems, low or high blood pressure, kidney or liver issues, or those taking nitrates should avoid tadalafil, as it can cause serious complications. Side effects may include headache, dizziness, flushing, or digestive upset. Consulting a healthcare provider before use is essential to ensure safety and proper dosing. Using the medication responsibly under medical supervision minimizes risks and improves effectiveness.