How to Choose the Perfect mRNA Plasmid?
mRNA vaccine is becoming more and more popular in the field of vaccine development, due to its high delivery rate, feasibility of manufacturing in large scale, and its higher safety and efficacy. mRNA is usually produced by in vitro transcription using plasmid as templates. Therefore, plasmid for mRNA is regarded as raw material, which is the same with the plasmid for CAR-T.
Still, people are highly aware of the quality of mRNA plasmid, and pay attention to the traceability of the plasmid as well. Unlike plasmid for CAR-T, supercoiled plasmid is not necessary for plasmid for mRNA, as the plasmid will be linearized for the following work. However, just the similar with plasmid for CAR-T, plasmid for mRNA, as is being regarded as raw material, should also be manufactured under compliance, and clear history of manufacturing is supposed to be guaranteed.
GenScript ProBio has already assisted over 10 customers to provide them with high quality plasmid for mRNA, and keeps developing platform and accumulating experience to better offer plasmid for mRNA and CAR-T plasmid.
