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Malegra 100 mg is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, a PDE5 inhibitor that helps increase blood flow to the penis during sexual arousal, enabling a firm and lasting erection. Sildenafil in Malegra 100 mg works by blocking the enzyme phosphodiesterase type 5 (PDE5), which breaks down cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the blood vessels of the penis, allowing increased blood flow.