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Cenforce 25 mg, which contains sildenafil citrate, is a medication used to treat erectile dysfunction (ED). There are certain situations and conditions where it is advisable to avoid taking Cenforce 25 mg or any medication containing sildenafil citrate. Here are some considerations:

1. Nitrates: Avoid taking Cenforce 25 mg if you are taking nitrates or nitric oxide donors (such as nitroglycerin) for chest pain (angina) or heart conditions. Combining sildenafil with nitrates can cause a dangerous drop in blood pressure.

2. Alpha-Blockers: If you are taking alpha-blockers (such as doxazosin, tamsulosin) for high blood pressure or prostate conditions, use caution with sildenafil. These medications can also lower blood pressure, and combining them with sildenafil can amplify this effect.

3. Severe Cardiovascular Issues: Individuals with severe cardiovascular disease, recent heart attack or stroke, unstable angina, or uncontrolled hypertension should avoid Cenforce 25 Mg or use it only under strict medical supervision.

4. Liver or Kidney Disease: If you have severe liver or kidney impairment, consult with your healthcare provider before taking Cenforce 25 mg. Adjustments to the dosage may be necessary to prevent potential complications.

5. Hypersensitivity: Avoid Cenforce 25 mg if you have a known hypersensitivity or allergy to sildenafil citrate or any inactive ingredients in the medication.

6. Vision Issues: If you have a history of non-arteritic anterior ischemic optic neuropathy (NAION) or other vision problems, use caution with sildenafil as it has been associated with rare instances of vision changes.

7. Priapism: Avoid sildenafil if you have a predisposition to priapism (prolonged erections lasting more than 4 hours), as sildenafil can increase the risk.

Always consult with your healthcare provider before starting or stopping any medication, including Cenforce 25 mg. They can provide guidance based on your medical history and help determine the safest and most effective treatment for your condition.