Neuroplasticity is the brain’s ability to reorganize itself by forming new neural connections, and it plays a vital role in stroke rehabilitation. After a stroke, damaged areas of the brain can potentially reroute functions to healthy parts, allowing for recovery of movement, speech, and other skills. Rehabilitation programs designed to enhance neuroplasticity involve repetitive, task-specific exercises that challenge the brain to learn new ways to perform tasks. Therapies like constraint-induced movement therapy, where the unaffected limb is restrained to encourage use of the affected one, capitalize on neuroplasticity principles. Early and intensive rehab increases the likelihood of regaining function through neuroplastic changes.