Lenalidomide is an oral medication used primarily to treat various forms of cancer, including multiple myeloma, myelodysplastic syndromes, and mantle cell lymphoma. It is an immunomodulatory drug, meaning it helps to enhance the body's immune system, while also having anti-angiogenic and anti-inflammatory effects. These properties make it effective in targeting cancerous cells and reducing tumor growth. Lenalidomide works by affecting the tumor microenvironment, altering immune system activity, and influencing the growth of blood vessels that supply tumors.

The drug is often used in combination with other therapies, such as dexamethasone, to increase its effectiveness, particularly in the treatment of multiple myeloma. In cases of myelodysplastic syndromes, Lenalidomide has shown efficacy in improving blood cell counts, particularly in patients with a deletion of chromosome 5q, a genetic abnormality often associated with these conditions. Additionally, Lenolidomide price has been explored in clinical trials for other types of cancers, including non-Hodgkin lymphoma and solid tumors, though its primary approved uses remain in hematologic malignancies.

Lenalidomide is generally well tolerated, but it can cause side effects, which may include fatigue, constipation, nausea, and low blood cell counts, such as anemia and neutropenia. More serious side effects, though rare, include blood clots, liver damage, and birth defects if used during pregnancy. Due to these risks, patients taking Lenalidomide are often closely monitored with regular blood tests. The drug is also associated with a risk of secondary cancers, such as acute myelogenous leukemia, particularly when used in combination with other agents like chemotherapy.

Given its powerful effects, Lenalidomide is typically prescribed under strict medical supervision, and patients are required to adhere to safety protocols, including contraception for both male and female patients of reproductive age, to prevent pregnancy. Despite its side effect profile, Lenalidomide remains a critical part of the treatment landscape for several cancer types.