Vidalista 80 mg, which contains tadalafil, has a slower onset compared to other erectile dysfunction (ED) medications like sildenafil (Viagra) because of the way it is metabolized and how it interacts with the body. Tadalafil has a longer half-life, remaining active in the body for up to 36 hours, which is why it is often referred to as the "weekend pill." While sildenafil typically begins to work within 30 to 60 minutes, tadalafil can take up to 1-2 hours to show its effects. The slower onset is a trade-off for its extended duration of action, allowing for more flexibility in timing. This longer action makes tadalafil suitable for those seeking spontaneity in sexual activity.