Vriligy 60 mg, which contains dapoxetine, is generally taken with or without food. However, taking it with food may help reduce the risk of side effects such as nausea or dizziness, which are relatively common with Vriligy 60 mg medication. While food does not significantly affect the absorption or effectiveness of dapoxetine, it can help create a more stable environment in the stomach, especially for individuals who may have gastrointestinal sensitivity. It is important to take Vriligy with a full glass of water and to avoid alcohol, as it can increase the risk of side effects such as fainting or low blood pressure. Always follow your doctor's instructions.