Malegra 25 mg, which contains sildenafil citrate, is best taken approximately 30 to 60 minutes before anticipated sexual activity. The medication works by enhancing blood flow to the penis, aiding in achieving and maintaining an erection when sexually aroused. Malegra 25 mg should be taken on an empty stomach for optimal absorption, as high-fat meals may delay its effects. The effectiveness typically lasts for about four to six hours. It is important not to exceed one dose within a 24-hour period. Always follow your doctor’s guidance regarding dosage and timing, especially if you have any underlying health conditions or take other medications.