Malegra 100 mg, which contains sildenafil citrate, is generally considered safe for many men when used under medical supervision. However, long-term use should only be undertaken after consulting a healthcare provider, especially if the user has underlying conditions like heart disease, liver or kidney issues, or low blood pressure. While many users tolerate it well over time, continuous or frequent use may lead to side effects such as headaches, visual disturbances, nasal congestion, or gastrointestinal upset. In rare cases, long-term use may contribute to more serious complications like hearing or vision loss or priapism (a prolonged, painful erection). There is limited research on the effects of daily, long-term use beyond clinical guidelines. Therefore, regular monitoring and periodic evaluation by a doctor are essential to ensure Malegra 100 remains safe and effective over time.