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As COVID-19 tormented many and left others dazed, the number of clinical trials dramatically increased from 2000 onwards.... moreAs COVID-19 tormented many and left others dazed, the number of clinical trials dramatically increased from 2000 onwards. Another change is that quality assurance regulations have become tighter. Clinical database management systems tools have become more necessary for enhancing data quality, which is a key component to the success of clinical trials.