Similarities Between Soft Capsules And Hard Capsules

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Similarities Between Soft Capsules And Hard Capsules

Posté par Hua Guang     21 décembre 2021    

Corps

The ingredients in the soft capsule shell are roughly similar to those in the Empty Hard Capsules shell. The composition of the capsule shell mainly includes rubber, plasticizer, water, and additives. In addition to meeting the requirements of Pharmacopoeia, the quality of gelatin should also meet the requirements of gel strength and viscosity. For example, the freezing force is 150~2500, and the viscosity is 25~45mpa.s. For drugs with strong hygroscopicity, high freezing force and low strength should be used. Gelatin. Titanium dioxide is used as the masking agent, and its dosage is 2-12g per kg of gelatin. Flavoring agents such as 5% sucrose can be added to increase sweetness, chew, and adjust hardness. The preservative uses a mixture of methyl p-hydroxybenzoate (1.6%) and propyl p-hydroxybenzoate (0.04%). The shell contains a certain amount of water, and the general finished product is 6% to 13%.

Features
(1) Liquid oily substances can be directly enclosed in capsules, without the need to use additives such as adsorption and inclusion, and the content of oily substances in soft capsules is as high as 60%-85%, while the content of inclusions is generally below 50%.
(2) If thick gelatin is used to make the film, it can be completely hermetically sealed, the capsule has high strength and film covering properties, and the contents can be kept stable for a long time. According to measurements, the gelatin film has more than 30 times the oxygen shielding properties of polyethylene film. It is very stable to oxygen in the air and can prevent air oxidation and moisture absorption.
(3) After ingestion, the contents are released quickly, and the utilization rate in the body is high.
(4) The content has good uniformity and the content deviation is very low.
(5) It can cover the peculiar smell and smell of some contents, especially for some functional health foods and pharmaceutical applications. Because it is different from general foods, it has many peculiar smells and smells.
(6) The taste, color, fragrance, transparency, and gloss of the capsule film can be freely selected. Compared with other round products, it has a good gloss and is eye-catching.
(7) The round airtight container is a clean container that cannot be mixed with foreign matter during circulation.
(8) For low boiling points, volatile substances can be stored stably. Moreover, some contraindicated ingredients can be added separately to the two-layer content.
(9) There is no need to add binders, foaming agents, and other additives. Generally, soft capsules are made of gelatin, glycerin, and water, which are edible natural products.
(10) Soft Capsules should meet the following requirements during production and storage: small-dose drugs should be diluted with a suitable diluent first, and mixed uniformly; they should have a clean appearance, no sticking, deformation or cracking, and no odor; Unless otherwise specified, it should be sealed and stored.

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