When oral Cannabis is consumed, there is a low (6% -20%) and flexible oral bioavailability. half-life 20 to 30 hours. Taken orally, delta-9-THC is initially metabolized in the liver to 11-OH-THC, a potent psychoactive metabolite.

Inhaled cannabinoids enter the bloodstream rapidly with a high concentration of 2 to 10 minutes, Cannabis edible declining for a period of 30 minutes and a subsequent generation of psychoactive 11-OH metabolite.

Cannabinoids are

Known to interact with the hepatic cytochrome P450 enzyme system. 3 weeks later the same drug-related Cannabis treatment is taken as herbal tea for 15 consecutive days, starting 12 days before the second treatment. [4] The administration of Cannabis did not have a significant effect on the exposure to and approval of irinotecan or docetaxel, although the herbal route of administration may not produce the effects of inhaling or ingesting soluble cannabinoids.

High concentrated THC or cannabidiol (CBD) extracted oil is illegally developed as a potential cancer treatment. [5] These oils have not been tested in any clinical trials for function or cancer safety. Because CBD has the potential to inhibit certain cytochrome P450 enzymes, high concentrated CBD oils are used in conjunction with conventional therapies digested by these enzymes that may increase toxicity or Weed edibles the effectiveness of these therapies. [6,7]

The Risk of Cancer

• Numerous studies have produced
• Conflicting evidence regarding
• The risks of various cancers
• Associated with smoking Cannabis

A combined analysis of three studies of a group of men in northwestern Africa (430 cases and 778 controls) showed a significantly increased risk of lung cancer among smokers who also smoked Cannabi. [8]

A large, retrospective

Study of 64,855 men aged 15 to 49 from the United States found that marijuana use Cannabis gummies not associated with tobacco-related cancer and a number of other common diseases. However, research has found that, in nonsmokers, former users of Cannabis were associated with an increased risk of prostate cancer.

A population-based

Study of 611 lung cancer patients showed that chronic exposure to Cannabis was not associated with an increased risk of lung cancer or other advanced aerodigestive tract and did not find a positive association with any type of cancer (oral, pharyngeal, laryngeal, lung. , or throat) when correcting a few confusing things, including smoking.

A systematic review of 19 randomized controlled trials examining dangerous or malignant lung lesions in people 18 years of age or older who inhaled Cannabis concluded that experimental studies failed to show statistically significant Weed candy between marijuana inhalation and lung cancer after adjusting for tobacco use.

In a review of published meta-analyzes, a report by the National Academies of Sciences, Engineering, and Medicine (NASEM) concluded that there is limited evidence that there is no statistically significant association between smoking Cannabis and the incidence of lung cancer.